BDBM523252 (1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin-2-yl)- cyclohexane-1- carboxamide::US11135207, Example 32

SMILES Oc1ccc(NC(=O)[C@H]2CC[C@@H](CC2)c2ccc(Cl)cc2)nc1

InChI Key InChIKey=LUTGRGXXDHJUPS-MQMHXKEQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523252   

TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523252((1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin...)
Affinity DataIC50:  1nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523252((1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin...)
Affinity DataIC50:  1nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent