BDBM523904 2-amino-N-[1-(5-cyano-3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-4-piperidyl]-5-fluoro-pyridine-4-carboxamide::US11136325, Compound 6

SMILES Cc1c[nH]c2ncc(C#N)c(N3CCC(CC3)NC(=O)c3cc(N)ncc3F)c12

InChI Key InChIKey=JCALSJNCSPPKCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523904   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523904(2-amino-N-[1-(5-cyano-3-methyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  1.05nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523904(2-amino-N-[1-(5-cyano-3-methyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  1.05nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent