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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM523904'
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523904(2-amino-N-[1-(5-cyano-3-methyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  1.05nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523904(2-amino-N-[1-(5-cyano-3-methyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  1.05nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent