BDBM567750 US11420968, Example F112

SMILES CCc1ccccc1[C@@H]1CCCN1C1CC2(C1)CN(C2)c1ccc(C(=O)NS(=O)(=O)c2ccc(NC[C@H]3COCCO3)c(c2)[N+]([O-])=O)c(Oc2cnc3[nH]ccc3c2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 567750   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM567750(US11420968, Example F112)
Affinity DataIC50:  42nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-X protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM567750(US11420968, Example F112)
Affinity DataIC50:  0.0450nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2/Bcl-X protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent