BDBM57475 2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperidinyl}methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione hydrochloride::2-[[1-(2-hydroxy-3-naphthalen-2-yloxypropyl)piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-[[1-(3-naphthalen-2-yloxy-2-oxidanyl-propyl)piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-[[1-[2-hydroxy-3-(2-naphthalenyloxy)propyl]-4-piperidinyl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-[[1-[2-hydroxy-3-(2-naphthoxy)propyl]-4-piperidyl]methyl]benzo[de]isoquinoline-1,3-quinone;hydrochloride::MLS000572681::SMR000194544::cid_2891886

SMILES OC(COc1ccc2ccccc2c1)CN1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1

InChI Key InChIKey=TXPRPLRWADQUKQ-UHFFFAOYSA-N

Data  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 57475   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataEC50:  1.79E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataIC50:  1.50E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataEC50:  1.85E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataEC50: >1.03E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataIC50:  7.69E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMelanocortin receptor 4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataEC50:  6.31E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Mus musculus (Mouse))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57475(2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperi...)
Affinity DataIC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay