BDBM627228 3-[3-(difluoromethoxy)phenyl]- N-(3-methyl-1,1-dioxo-thietan-3- yl)-1-sec-butyl-pyrazolo[4,3- b]pyridine-6-carboxamide (slower eluting in AD-H column, 20% MeOH/CO2)::US11787810, Example 66b::US20240059700, Example 66b
SMILES CC[C@H](C)n1nc(-c2cccc(OC(F)F)c2)c2ncc(cc12)C(=O)NC1(C)CS(=O)(=O)C1
InChI Key InChIKey=QZLSVGCRYDNHFG-ZDUSSCGKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 627228
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair