BDBM627264 4-cyano-3-(3- (difluoromethoxy)phenyl)-1- isopropyl-N-(3-methyl-1,1- dioxidothietan-3-yl)-1H-indazole- 6-carboxamide::US11787810, Example 91::US20240059700, Example 91

SMILES CC(C)n1nc(-c2cccc(OC(F)F)c2)c2c(cc(cc12)C(=O)NC1(C)CS(=O)(=O)C1)C#N

InChI Key InChIKey=DOYNKLBHFRTWGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 627264   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627264(4-cyano-3-(3- (difluoromethoxy)phenyl)-1- isopropy...)
Affinity DataIC50:  2nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627264(4-cyano-3-(3- (difluoromethoxy)phenyl)-1- isopropy...)
Affinity DataIC50:  2nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent