BDBM633317 US20190276450, Example 12b.2
SMILES CO[C@]1(CCOC1)c1cc(cc(n1)-c1cn([C@@H]2CCOC2)c2cnc(NC(N)=O)cc12)C(F)F
InChI Key InChIKey=VQIKDEUGSJBAPP-FATZIPQQSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 633317
Affinity DataEC50: 4.00E+4nMAssay Description:IL-6 is known to transduce its signal through IL-6 receptor via Jak1. Activity against Jak was therefore measured by determining inhibition of IL-6 i...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair