BDBM633338 US20190276450, Example 17.5
SMILES CO[C@]1(CCOC1)c1cc(C)cc(n1)-c1cn([C@@H]2C[C@@H](C2)C#N)c2cnc(NC(C)=O)cc12
InChI Key InChIKey=CNASVIXKXKUKCD-ATLLOTDBSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 633338
Affinity DataEC50: 3.20E+4nMAssay Description:IL-6 is known to transduce its signal through IL-6 receptor via Jak1. Activity against Jak was therefore measured by determining inhibition of IL-6 i...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair