BDBM636432 N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}-2-(4-fluorophenyl)acetamide (Racemate)::US20230365554, Example 1::US20230365554, Example 2::US20230365554, Example 3

SMILES CCC1CNC(=O)c2c(Nc3ccccc3)c([nH]c12)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 636432   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  1.5nMAssay Description:CSNK1A1-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  5.5nMAssay Description:CSNK1D-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  3.30nMAssay Description:CSNK1A1-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  5.20nMAssay Description:CSNK1D-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  320nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and a fragment of human EGFR (amino acids R669 to A1210), expressed in Sf9 in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  10nMAssay Description:CSNK1D-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  57nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and a fragment of human EGFR (amino acids R669 to A1210), expressed in Sf9 in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  190nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and a fragment of human EGFR (amino acids R669 to A1210), expressed in Sf9 in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM636432(N-{4-[3-anilino-7-ethyl-4-oxo-4,5,6,7-tetrahydro-1...)
Affinity DataIC50:  3.80nMAssay Description:CSNK1A1-inhibitory activity of compounds of the present invention in presence of 1 μM adenosine-tri-phosphate (ATP) was quantified employing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent