BDBM7238 (3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3-dihydro-1H-indol-2-one::3-(3H-Imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-indol-2-one::SU9516::cid_5289419::imidazole indolinone driv.
SMILES COc1ccc2NC(=O)C(=Cc3cnc[nH]3)c2c1
InChI Key InChIKey=QNUKRWAIZMBVCU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 7238
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well microtit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair