BDBM84533 Alsterpaullone derivative, 7::BDBM50375663

SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccc(CCC#N)cc-34)c2c1

InChI Key InChIKey=UBLFSMURWWWWMH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 84533   

TargetGlycogen synthase kinase-3 beta(Human)
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 0.230nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 316nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 316nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed