BDBM86453 CAS_73573-87-2::Formoterol::NSC_3083544

SMILES COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1

InChI Key InChIKey=BPZSYCZIITTYBL-UHFFFAOYSA-N

Data  12 KI  8 IC50  1 Kd  19 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 86453   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM86453(CAS_73573-87-2 | Formoterol | NSC_3083544)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM86453(CAS_73573-87-2 | Formoterol | NSC_3083544)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM86453(CAS_73573-87-2 | Formoterol | NSC_3083544)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM86453(CAS_73573-87-2 | Formoterol | NSC_3083544)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM86453(CAS_73573-87-2 | Formoterol | NSC_3083544)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank