BDBM9468 1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole::CHEMBL376371::Fluorenyl deriv. 17

SMILES c1ncn(n1)C1(c2ccccc2-c2ccccc12)c1ccccc1

InChI Key InChIKey=KVOFEYRUEAXEJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9468   

TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9468(1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole | C...)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9468(1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole | C...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9468(1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole | C...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed