Compile Data Set for Download or QSAR
Report error Found 265 Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6'
LigandChemical structure of BindingDB Monomer ID 429751BDBM429751(US10550100, Compound 72 | 5-(3-(4-(4- fluoro-3,5- ...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471740BDBM471740((R)-5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) pip...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429750BDBM429750(US10550100, Compound 71 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471743BDBM471743(5-cyclopropyl-5- [3-[(3S)-4-(3,4- difluoro-5- meth...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471736BDBM471736(5-cyclopropyl-5- [3-[4-(3,4- difluoro-5- methoxy- ...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429752BDBM429752(US10550100, Compound 73 | 5-(3-(4-(3- chloro-4- fl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429747BDBM429747(US10550100, Compound 68 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429748BDBM429748(US10550100, Compound 69 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429745BDBM429745(US10550100, Compound 66 | (R)-5-(3-(4-(3- chloro-5...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429741BDBM429741(US10550100, Compound 62 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429740BDBM429740(US10550100, Compound 61 | (R)-5-(3-(4- (4,5-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429768BDBM429768(US10550100, Compound 88 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429767BDBM429767(US10550100, Compound 87 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471788BDBM471788((5S)-5- cyclopropyl- 5-[3-[(3S)-4-(3,4- difluoro-5...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429770BDBM429770(US10550100, Compound 90 | (5R)-5-[3-[4- [4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429769BDBM429769(US10550100, Compound 89 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429763BDBM429763(US10550100, Compound 84 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471771BDBM471771(5-[3-[(3S)-4-(4- chloro-3,5- dimethoxy- phenyl)- 3...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429765BDBM429765(US10550100, Compound 85 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471775BDBM471775(5-[3-[4-(4-chloro- 3,5-dimethoxy- phenyl) piperazi...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429759BDBM429759(US10550100, Compound 80 | (5R)-5-[3-[4- (3-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429758BDBM429758(US10550100, Compound 79 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471769BDBM471769(5-cyclopropyl-5- [(2S)-3-[(3S)-4- (3,4-difluoro-5-...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429761BDBM429761(US10550100, Compound 82 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471764BDBM471764((5S)-5- cyclopropyl- 5-[(2S)-3-[4-(3- fluoro-5-met...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429760BDBM429760(US10550100, Compound 81 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471766BDBM471766((5R)-5-[(2S)-3-[4- (3-fluoro-5- methoxy- phenyl) p...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471761BDBM471761(5-[3-[(3S)-4-(4- chloro-3-methoxy- phenyl)-3-methy...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471757BDBM471757(5-[3-[(3S)-4-(3,4- difluoro-5- methoxy-phenyl)- 3-...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429780BDBM429780(US10550100, Compound 104 | 5-[3-[4-(4- chloro-3-et...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471801BDBM471801(5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) piperaz...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429779BDBM429779(US10550100, Compound 103 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471827BDBM471827(5-[3-[(3S)-4-(3- chloro-4-fluoro-5- methoxy-phenyl...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429782BDBM429782(US10550100, Compound 106 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471799BDBM471799(5-[3-[4-(3-chloro- 4-fluoro-5- methoxy- phenyl) pi...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429781BDBM429781(US10550100, Compound 105 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471800BDBM471800(5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) piperaz...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429776BDBM429776(US10550100, Compound 100 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471797BDBM471797(5-[3-[4-(3,4- dichloro-5- methoxy- phenyl) piperaz...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471798BDBM471798(5-[3-[(3S)-4-(3,4- difluoro-5- methoxy-phenyl)- 3-...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429778BDBM429778(US10550100, Compound 102 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471795BDBM471795(5-[3-[(3S)-4-(3,4- difluoro-5- methoxy-phenyl)- 3-...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471796BDBM471796(5-[3-[(3S)-4-(4- chloro-3-methoxy- phenyl)-3-methy...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429772BDBM429772(US10550100, Compound 96 | (5R)-5-[3-[4- (4,5-dichl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471933BDBM471933(5-[3-[(3S)-4-(4- chloro-3,5- dimethoxy- phenyl)- 3...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429797BDBM429797(US10550100, Compound 95 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429774BDBM429774(US10550100, Compound 98 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471793BDBM471793(5-[3-[(3S)-4-(3,4- difluoro-5- methoxy-phenyl)- 3-...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 429773BDBM429773(US10550100, Compound 97 | 5-[3-[4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 471794BDBM471794(5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) piperaz...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

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