Compile Data Set for Download or QSAR
Report error Found 3831 Enz. Inhib. hit(s) with Target = 'Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B'
LigandChemical structure of BindingDB Monomer ID 279100BDBM279100(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 580556BDBM580556(US11491140, Example 131 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 501501BDBM501501(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279100BDBM279100(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Affinity DataIC50: 0.0420nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279100BDBM279100(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279100BDBM279100(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279100BDBM279100(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Affinity DataIC50: 0.0420nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 580557BDBM580557(US11491140, Example 132 | 5-(2-ethoxy-3-pyridyl)-3...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 501502BDBM501502(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[1- methylimidaz...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279101BDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279101BDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279101BDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279101BDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50: 0.0450nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279101BDBM279101(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...)
Affinity DataIC50: 0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50150119BDBM50150119(CHEMBL3769414)
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of PDE1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279063BDBM279063(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Affinity DataIC50: 0.0650nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279017BDBM279017(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Affinity DataIC50: 0.0690nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278972BDBM278972(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Affinity DataIC50: 0.0710nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 501505BDBM501505(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridy...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279104BDBM279104(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3-pyridyl...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 279114BDBM279114(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

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