Compile Data Set for Download or QSAR
maximum 50k data
Found 161 Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 1'
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of EphB1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50244430(9-(2,6-dimethylstyryl)-N-(4-(dimethylphosphoryl)ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EphB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human EPHB1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  30nMAssay Description:Inhibition of EphB1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  60.3nMAssay Description:Inhibition of human EPHB1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  128nMAssay Description:Inhibition of EPHB1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50563891(CHEMBL4793380)
Affinity DataIC50:  388nMAssay Description:Inhibition of recombinant human EphB1 (564 to end residues) using KVEKIGEGTYGVVYK as substrate incubated for 40 mins in presence of [gamma-33ATP] by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50358591(CHEMBL1923983)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of EphB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of EPHB1-mediated proliferation of mouse BAF3 cells transformed with TEL-Kinase constructMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50428059(CHEMBL2322989)
Affinity DataIC50:  3.80E+3nMAssay Description:Displacement of ephrin-B1-Fc from EphB1 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50509949(CHEMBL4475216 | US11667631, Example 29)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphB1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EPHB1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EPHB1 using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of EPHB1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EphB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human EphB1 (564 to end residues) using KVEKIGEGTYGVV as substrate after 40 mins in presence of [gamma-33ATP] by radiometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50182493(CHEMBL3818247 | US9512121, 22)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EPHB1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Rattus norvegicus)
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of biotinylated ephrin-B1-Fc from rat EphB1 Fc preincubated for 1 hr followed by ephrin-B1-FC addition and measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)
Affinity DataKd:  180nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataKd:  4.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  0.450nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)
Affinity DataKd:  330nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  3.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)
Affinity DataKd:  240nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  480nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKd:  1.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  290nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  590nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding affinity to EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  240nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd:  550nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  240nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  1.70E+3nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  540nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  1.40E+3nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  960nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd:  7.30E+3nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataKd:  4.20E+3nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM15244(5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...)
Affinity DataKd:  1.60E+3nMAssay Description:Average Binding Constant for EPHB1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to EPHB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 161 total ) | Next | Last >>
Jump to: