Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with Target = 'Ferrochelatase, mitochondrial'
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185145(7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-(3-phenylm...)
Affinity DataKd:  4.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataEC50:  5.01E+3nMAssay Description:Stabilization of FECH in human K562 cells after 1 hr by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataKd:  3.10E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50429701(AZD-2014 | CHEMBL2336325 | US9102670, 1ap)
Affinity DataKd:  3.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50246253(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(me...)
Affinity DataKd:  2.60E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50348452(AZD-8055 | CHEMBL1801204 | US9102670, 1a)
Affinity DataKd:  6.20E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185147((Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-...)
Affinity DataKd:  3.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185148((3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,...)
Affinity DataKd:  3.00E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataKd:  2.80E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM31340(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Affinity DataKd:  2.30E+4nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)
Affinity DataKd:  3.80E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataKd:  3.50E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataKd:  700nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataKd:  3.10E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKd:  9.30E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd:  1.00E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50315769(3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...)
Affinity DataKd:  1.70E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKd:  2.70E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185150(3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]...)
Affinity DataKd:  2.20E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50347659(CHEMBL1802916 | MK-2461)
Affinity DataKd:  2.10E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataKd:  2.80E+4nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataKd:  3.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50161957(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(p...)
Affinity DataKd:  5.10E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  1.70E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185151(4-[(5Z)-4-amino-5-(7-methoxyindol-2-ylidene)-1H-im...)
Affinity DataKd:  4.50E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataKd:  1.00E+4nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM60665(BDBM50249542 | US9145414, R406 | US9212178, R406)
Affinity DataKd:  3.60E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd:  3.20E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataKd:  1.30E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFerrochelatase, mitochondrial [R115L](Homo sapiens (Human))
Technical University Of Munich

LigandPNGBDBM185146(6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-y...)
Affinity DataKd:  6.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed