Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta [7-25]'
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6870BDBM6870(4-({5-amino-1-[(3-methylthiophen-2-yl)carbonyl]-1H...)
Affinity DataIC50: 26nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6867BDBM6867(4-({5-amino-1-[(2,6-difluoro-3-methylphenyl)carbon...)
Affinity DataIC50: 31nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 41nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6878BDBM6878(5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphen...)
Affinity DataIC50: 140nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6421BDBM6421(N-(3-chlorophenyl)-6-(5-{[3-(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 196nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6419BDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 318nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6416BDBM6416(3-[[5-[6-[(3-chlorophenyl)amino]pyrazinyl]-3-pyrid...)
Affinity DataIC50: 478nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6416BDBM6416(3-[[5-[6-[(3-chlorophenyl)amino]pyrazinyl]-3-pyrid...)
Affinity DataIC50: 478nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7868BDBM7868(2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one |...)
Affinity DataIC50: 500nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7876BDBM7876(2-bromo-1-(4-bromophenyl)ethan-1-one | p-bromophen...)
Affinity DataIC50: 500nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6420BDBM6420(N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...)
Affinity DataIC50: 606nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7804BDBM7804(1-benzyl-2,5-dihydro-1H-pyrrole-2,5-dione | Maleim...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7869BDBM7869(2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one |...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7856BDBM7856(2-chloro-1-(2,4,5-tribromothiophen-3-yl)ethan-1-on...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7877BDBM7877(2-bromo-1-(4-chlorophenyl)ethan-1-one | Halomethyl...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7879BDBM7879(CHEMBL103009 | 2-bromo-1-(4-methoxyphenyl)ethan-1-...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7859BDBM7859(2-chloro-1-[4-(2-chloroacetyl)thiophen-2-yl]ethan-...)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7852BDBM7852(ethyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7807BDBM7807(1-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-2,5-dione...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7792BDBM7792(4-(4-Methoxylphenyl)-2-methyl-1,2,4-thiadiazolidin...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7781BDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7857BDBM7857(1-(2-bromo-4,5-dichlorothiophen-3-yl)-2-chloroetha...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7784BDBM7784(2-methyl-4-phenyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7881BDBM7881(2-bromo-1-(4-nitrophenyl)ethan-1-one | Halomethyl ...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7853BDBM7853(2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one ...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7806BDBM7806(N-(p-Methoxy-benzyl)-maleimide | 1-[(4-methoxyphen...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7874BDBM7874(2-chloro-1-(4-chlorophenyl)ethan-1-one | Halomethy...)
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7878BDBM7878(2-bromo-1-(4-methylphenyl)ethan-1-one | Halomethyl...)
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7880BDBM7880(2-bromo-1-(4-phenylphenyl)ethan-1-one | CHEMBL4130...)
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7805BDBM7805(ethyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acet...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7854BDBM7854(1-(4-bromothiophen-2-yl)-2-chloroethan-1-one | Chl...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7808BDBM7808(1-[2-(4-methoxyphenyl)ethyl]-2,5-dihydro-1H-pyrrol...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7793BDBM7793(2-methyl-4-(1-naphthyl)-1,2,4-thiadiazolidine-3,5-...)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7809BDBM7809(N-(3-Phenyl-propyl)-maleimide | 1-(3-phenylpropyl)...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7810BDBM7810(N-(5-Phenyl-pentanyl)-maleimide | 1-(5-phenylpenty...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7785BDBM7785(4-(4-Bromophenyl)-2-methyl-1,2,4-thiadiazolidine-3...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7788BDBM7788(4-(4-Chlorophenyl)-2-methyl-1,2,4-thiadiazolidine-...)
Affinity DataIC50: 4.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7789BDBM7789(4-(4-Fluorophenyl)-2-methyl-1,2,4-thiadiazolidine-...)
Affinity DataIC50: 4.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7786BDBM7786(4-(3-Bromophenyl)-2-methyl-1,2,4-thiadiazolidine-3...)
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 6417BDBM6417(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)
Affinity DataIC50: 4.02E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7803BDBM7803(1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione | Maleim...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7870BDBM7870(2-chloro-1-(2,5-dichlorothiophen-3-yl)ethan-1-one ...)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7791BDBM7791(4-(4-Methylphenyl)-2-methyl-1,2,4-thiadiazolidine-...)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7875BDBM7875(2-bromo-1-phenylethan-1-one | CHEMBL102953 | Halom...)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7861BDBM7861(2-chloro-1-[4-(2-chloroacetyl)-5-methylthiophen-2-...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7865BDBM7865(2-chloro-1-[4-(2-chloroacetyl)-3-methylthiophen-2-...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7774BDBM7774(4-Ethyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7851BDBM7851(2-Ethyl-4-phenyl-1,2,4-thiadiazolidine-3,5-dione |...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7790BDBM7790(2-methyl-4-[4-(trifluoromethyl)phenyl]-1,2,4-thiad...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 7797BDBM7797(4-Benzyl-2-ethyl-5-oxo-1,2,4-thiadiazolidine-3-thi...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
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