Compile Data Set for Download or QSAR
Report error Found 225 Enz. Inhib. hit(s) with Target = 'Neuromedin-U receptor 1'
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291718BDBM50291718(CHEMBL4174679)
Affinity DataIC50: 0.0370nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085928BDBM50085928(CHEMBL3425593)
Affinity DataEC50:  0.0830nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291719BDBM50291719(CHEMBL4165538)
Affinity DataIC50: 0.0860nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338535BDBM50338535(CHEMBL4162728)
Affinity DataIC50: 0.0920nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049421BDBM50049421(CHEMBL3315349)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291714BDBM50291714(CHEMBL4177021)
Affinity DataIC50: 0.150nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238691BDBM50238691(CHEMBL4088263)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239755BDBM50239755(CHEMBL4069151)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux after 18 hrs by Fluo-4 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238690BDBM50238690(CHEMBL4068681)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239756BDBM50239756(CHEMBL4105671)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux after 18 hrs by Fluo-4 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238704BDBM50238704(CHEMBL4095998)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291730BDBM50291730(CHEMBL4169726)
Affinity DataIC50: 0.290nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291730BDBM50291730(CHEMBL4169726)
Affinity DataIC50: 0.290nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291709BDBM50291709(CHEMBL4160825)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238694BDBM50238694(CHEMBL4098010)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238690BDBM50238690(CHEMBL4068681)
Affinity DataEC50:  0.320nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291699BDBM50291699(CHEMBL4175546)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291715BDBM50291715(CHEMBL4172552)
Affinity DataIC50: 0.340nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291696BDBM50291696(CHEMBL4164922)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238691BDBM50238691(CHEMBL4088263)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291701BDBM50291701(CHEMBL4165337)
Affinity DataIC50: 0.410nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239753BDBM50239753(CHEMBL4097923)
Affinity DataEC50:  0.420nMAssay Description:Agonist activity at mouse NMUR1 expressed in HEK293 cells assessed as induction of calcium mobilization after 18 hrs by Fluo-4 AM dye based FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049421BDBM50049421(CHEMBL3315349)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291730BDBM50291730(CHEMBL4169726)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291700BDBM50291700(CHEMBL4175953)
Affinity DataIC50: 0.510nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291730BDBM50291730(CHEMBL4169726)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataEC50:  0.540nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336621BDBM50336621(CHEMBL4170275)
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50500779BDBM50500779(CHEMBL3758577)
Affinity DataEC50:  0.562nMAssay Description:Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238694BDBM50238694(CHEMBL4098010)
Affinity DataEC50:  0.570nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50500783BDBM50500783(CHEMBL3759452)
Affinity DataEC50:  0.575nMAssay Description:Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238689BDBM50238689(CHEMBL4073946)
Affinity DataEC50:  0.690nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238707BDBM50238707(CHEMBL4059530)
Affinity DataEC50:  0.730nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336637BDBM50336637(CHEMBL4159554)
Affinity DataIC50: 0.75nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238689BDBM50238689(CHEMBL4073946)
Affinity DataEC50:  0.770nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049425BDBM50049425(CHEMBL3356083)
Affinity DataEC50:  0.810nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291716BDBM50291716(CHEMBL4161902)
Affinity DataIC50: 0.880nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238704BDBM50238704(CHEMBL4095998)
Affinity DataEC50:  0.960nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291717BDBM50291717(CHEMBL4164026)
Affinity DataIC50: 0.970nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238695BDBM50238695(CHEMBL4079986)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049421BDBM50049421(CHEMBL3315349)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291731BDBM50291731(CHEMBL4168753)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238693BDBM50238693(CHEMBL4063830)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2019
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291716BDBM50291716(CHEMBL4161902)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291698BDBM50291698(CHEMBL4167677)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049424BDBM50049424(CHEMBL3315348)
Affinity DataEC50:  1.70nMAssay Description:Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
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