Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with Target = 'Nuclear factor of activated T-cells, cytoplasmic 1'
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251509BDBM50251509(CHEMBL4064316 | US20250099442, Compound I.2)
Affinity DataEC50:  310nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251457BDBM50251457(CHEMBL4105629)
Affinity DataEC50:  1.59E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251452BDBM50251452(CHEMBL4077010)
Affinity DataEC50:  2.21E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251456BDBM50251456(CHEMBL4084955 | US20250099442, Compound I.1)
Affinity DataEC50:  2.98E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595362BDBM50595362(CHEMBL5174163)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of NFATC activity in HEK293T cells preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251453BDBM50251453(CHEMBL4079572)
Affinity DataEC50:  4.80E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251504BDBM50251504(CHEMBL4098505)
Affinity DataEC50:  4.85E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251477BDBM50251477(CHEMBL4075648)
Affinity DataEC50:  5.31E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251436BDBM50251436(CHEMBL4091320)
Affinity DataEC50:  6.90E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251476BDBM50251476(CHEMBL4095674)
Affinity DataEC50:  6.96E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251451BDBM50251451(CHEMBL4069163)
Affinity DataEC50:  7.58E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251475BDBM50251475(CHEMBL4090889)
Affinity DataEC50:  9.80E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595363BDBM50595363(CHEMBL5195853)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of NFATC activity in HEK293T cells preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595364BDBM50595364(CHEMBL5181607)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of NFATC activity in HEK293T cells preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251485BDBM50251485(CHEMBL4080488)
Affinity DataEC50:  2.08E+4nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251478BDBM50251478(CHEMBL4072138)
Affinity DataEC50:  2.17E+4nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetNuclear factor of activated T-cells, cytoplasmic 1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251486BDBM50251486(CHEMBL4066607)
Affinity DataEC50:  4.30E+4nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed