Compile Data Set for Download or QSAR
Report error Found 337 Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta'
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019866BDBM50019866(CHEMBL3286930)
Affinity DataKd:  0.0770nMAssay Description:Binding affinity to PDE-delta (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581180BDBM50581180(CHEMBL5081214)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529751BDBM50529751(CHEMBL4472979 | US10913710, Compound 16)
Affinity DataKd:  0.110nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581182BDBM50581182(CHEMBL5080391)
Affinity DataIC50: 0.126nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581183BDBM50581183(CHEMBL5087564)
Affinity DataIC50: 0.158nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529751BDBM50529751(CHEMBL4472979 | US10913710, Compound 16)
Affinity DataKd:  0.203nMAssay Description:Binding affinity to PDEdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529751BDBM50529751(CHEMBL4472979 | US10913710, Compound 16)
Affinity DataKd:  0.203nMAssay Description:Binding affinity to PDEdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581184BDBM50581184(CHEMBL5094110)
Affinity DataIC50: 0.251nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646344BDBM50646344(CHEMBL5594211)
Affinity DataKd:  0.300nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581185BDBM50581185(CHEMBL5076558)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581181BDBM50581181(CHEMBL5086895)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249988BDBM50249988(CHEMBL4061005)
Affinity DataKd:  0.600nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581186BDBM50581186(CHEMBL5088742)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581179BDBM50581179(CHEMBL5078680)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019865BDBM50019865(CHEMBL3286929)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to PDE-delta (unknown origin) by time-resolved fluorescence anisotropic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646343BDBM50646343(CHEMBL5595916)
Affinity DataKd:  1.30nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646349BDBM50646349(CHEMBL5595364)
Affinity DataKd:  1.5nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646348BDBM50646348(CHEMBL5592316)
Affinity DataKd:  1.60nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249988BDBM50249988(CHEMBL4061005)
Affinity DataKd:  2nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249988BDBM50249988(CHEMBL4061005)
Affinity DataKd:  2nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKd:  2.20nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249992BDBM50249992(CHEMBL4090695)
Affinity DataKd:  2.30nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKd:  3.80nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249987BDBM50249987(CHEMBL4082888)
Affinity DataKd:  4nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249979BDBM50249979(CHEMBL4061982)
Affinity DataKd:  4nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646335BDBM50646335(CHEMBL5595347)
Affinity DataKd:  4nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646345BDBM50646345(CHEMBL5591954)
Affinity DataKd:  4.5nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256259BDBM50256259(CHEMBL4073926)
Affinity DataKd:  4.5nMAssay Description:Inhibition of atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646342BDBM50646342(CHEMBL5583878)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646346BDBM50646346(CHEMBL5592494)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646337BDBM50646337(CHEMBL5592414)
Affinity DataKd:  6nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019850BDBM50019850(CHEMBL3286915)
Affinity DataKd:  6nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019852BDBM50019852(CHEMBL3286917)
Affinity DataKd:  7nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019849BDBM50019849(CHEMBL3286914)
Affinity DataKd:  7nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019843BDBM50019843(CHEMBL3286909)
Affinity DataKd:  7nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646341BDBM50646341(CHEMBL5591087)
Affinity DataKd:  7.20nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKd:  8nMAssay Description:Inhibition of atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKd:  8nMAssay Description:Binding affinity to PDEdelta (unknown origin) assessed as dissociation constant incubated for overnight by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKd:  8nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542203BDBM50542203(CHEMBL4635027)
Affinity DataKd:  8nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249989BDBM50249989(CHEMBL1387422)
Affinity DataKi:  8nMAssay Description:Binding affinity to PDE delta (unknown origin) assessed as dissociation constant measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249990BDBM50249990(CHEMBL4090022)
Affinity DataKd:  8nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019844BDBM50019844(CHEMBL3286910)
Affinity DataKd:  8nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583530BDBM50583530(CHEMBL5092661)
Affinity DataKi:  8.60nMAssay Description:Binding affinity to PDE delta (unknown origin) assessed as dissociation constant measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542198BDBM50542198(CHEMBL4647310)
Affinity DataKd:  9nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256251BDBM50256251(CHEMBL4100698)
Affinity DataKd:  9nMAssay Description:Inhibition of atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249980BDBM50249980(CHEMBL4091313)
Affinity DataKd:  9nMAssay Description:Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2019
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019846BDBM50019846(CHEMBL3286912)
Affinity DataKd:  9nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646334BDBM50646334(CHEMBL5590495)
Affinity DataKd:  9nMAssay Description:Displacement of fluorescein-labeled Atorvastatin from N-terminal His6 tagged human recombinant PDE6D extracted from Escherichia coli BL21 star (DE3) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019822BDBM50019822(CHEMBL3286902)
Affinity DataKd:  9nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
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