Compile Data Set for Download or QSAR
Report error Found 895 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger'
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058715BDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485565BDBM50485565(CHEMBL465179)
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234609BDBM50234609(Cariporide | HOE-642)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353115BDBM50353115(CHEMBL1829127)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353110BDBM50353110(CHEMBL1829122)
Affinity DataIC50: 0.0730nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353113BDBM50353113(CHEMBL1829125)
Affinity DataIC50: 0.0840nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353114BDBM50353114(CHEMBL1829126)
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353111BDBM50353111(CHEMBL1829123)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81818BDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196843BDBM50196843(CHEMBL3904640)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353097BDBM50353097(CHEMBL1829132)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201454BDBM50201454(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(pyr...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381682BDBM381682(US10272079, Compound 005 | US10272079, Compound 39)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human NHE3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381823BDBM381823(US10272079, Compound 002 | US10272079, Compound 18...)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353116BDBM50353116(CHEMBL1829128)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353098BDBM50353098(CHEMBL1829133)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353103BDBM50353103(CHEMBL1829139)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353102BDBM50353102(CHEMBL1829138)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378116BDBM50378116(CHEMBL1202327)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353105BDBM50353105(CHEMBL1829117)
Affinity DataIC50: 1.06nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353099BDBM50353099(CHEMBL1829134)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297583BDBM50297583(N''-[2-(1H-benzimidazol-2-ylthio)-5-nitro-2,3-dihy...)
Affinity DataIC50: 1.17nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601173BDBM50601173(CHEMBL5176968)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207580BDBM50207580(N-[3-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guan...)
Affinity DataIC50: 1.42nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353101BDBM50353101(CHEMBL1829137)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601180BDBM50601180(CHEMBL5170002)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381826BDBM381826(US10272079, Compound 003)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297577BDBM50297577(N''-[2-(1H-benzimidazol-2-ylthio)-2,3-dihydro-1H-i...)
Affinity DataIC50: 1.73nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297571BDBM50297571(N''-{2-[(5-nitro-1H-benzimidazol-2-yl)thio]-2,3-di...)
Affinity DataIC50: 1.74nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345911BDBM50345911(CHEMBL1789669 | CHEMBL1783852 | N-(diaminomethylen...)
Affinity DataIC50: 1.82nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297563BDBM50297563(N''-[2-(1,3-benzothiazol-2-ylthio)-6-methoxy-2,3-d...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297578BDBM50297578(2-{[(1E)-2-(1,3-benzothiazol-2-ylsulfanyl)-4,5,6-t...)
Affinity DataIC50: 1.98nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196811BDBM50196811(CHEMBL3967635)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471224BDBM50471224(CHEMBL64889)
Affinity DataIC50: 2nMAssay Description:Inhibition of NHE1 in human Platelet assessed as reduction in 22Na+ uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601178BDBM50601178(CHEMBL5202545)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471224BDBM50471224(CHEMBL64889)
Affinity DataIC50: 2nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297580BDBM50297580(N''-[2-(1,3-benzothiazol-2-ylthio)-5-chloro-2,3-di...)
Affinity DataIC50: 2.34nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297562BDBM50297562(N''-[2-(1,3-benzothiazol-2-ylthio)-5,6-dimethoxy-2...)
Affinity DataIC50: 2.44nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381826BDBM381826(US10272079, Compound 003)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104843BDBM50104843(N-[3-(3-Bromo-4-fluoro-phenyl)-2,2-dimethyl-cyclop...)
Affinity DataIC50: 3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426615BDBM426615(N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345911BDBM50345911(CHEMBL1789669 | CHEMBL1783852 | N-(diaminomethylen...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270005BDBM50270005(cid_1795 | CHEMBL1909809 | CHEMBL517986 | 5'-(N-et...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196812BDBM50196812(CHEMBL3946835)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196805BDBM50196805(CHEMBL3978001)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601172BDBM50601172(CHEMBL5183104)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207583BDBM50207583(N-[2-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guan...)
Affinity DataIC50: 4.05nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345917BDBM50345917(N-(diaminomethylene)-3-(N-methylsulfamoyl)-4-(1-(4...)
Affinity DataIC50: 4.48nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191852BDBM50191852(2-(5-(4-fluoro-3-methylphenyl)-4-(4-(4-methyl-1H-i...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471235BDBM50471235(CHEMBL416314)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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