Affinity DataKi: 110nM ΔG°: -39.7kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -39.5kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 310nM ΔG°: -37.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 450nM ΔG°: -36.2kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nM ΔG°: -34.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -34.0kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 1.29E+3nM ΔG°: -33.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+3nM ΔG°: -33.3kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 1.85E+3nM ΔG°: -32.7kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 4.07E+3nM ΔG°: -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 4.31E+3nM ΔG°: -30.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 4.32E+3nM ΔG°: -30.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 4.46E+3nM ΔG°: -30.5kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKi: 8.30E+3nM ΔG°: -29.0kJ/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.2 T: 2°CAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
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