Affinity DataKi: 0.0500nM ΔG°: -59.8kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -55.7kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -54.0kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 9.40nM ΔG°: -46.6kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -34.8kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 18.5nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human JNK2More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd
Curated by ChEMBL
Idenix Sarl, An Msd
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair