TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 10.3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 11.4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 85.3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 91.4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 114nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 268nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 304nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 389nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 640nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 657nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 681nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 2.92E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 4.68E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human plasma BuChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine liver DHFR measured every 1 min for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human HER2 incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli incubated for 15 mins and measured by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human EGFR incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human HER2 incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of bovine liver DHFR measured every 1 min for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of bovine DHFR after 2 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human plasma BuChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of DHFR (unknown origin) incubated for 2 to 5 mins by absorbance based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair