Compile Data Set for Download or QSAR
maximum 50k data
Found 47 with Last Name = 'weintraub' and Initial = 'hj'
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataKi:  0.320nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM81925(8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50009552(2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9...)
Affinity DataKi:  0.850nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataKi:  1.10nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421993(CHEMBL2113423)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50009552(2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9...)
Affinity DataKi:  2.40nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM42467((2R,3R,4S,5R)-2-(6-anilino-9-purinyl)-5-(hydroxyme...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM81925(8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-...)
Affinity DataKi:  3.90nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50228562(CHEMBL321505)
Affinity DataKi:  4.70nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50008413(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataKi:  21nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011216(1-Methyl-8-(1-methyl-2-phenyl-ethyl)-1,3-dipropyl-...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetp-hydroxybenzoate hydroxylase(Pseudomonas fluorescens)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50038194(2-Benzyloxy-4-hydroxy-benzoic acid | CHEMBL130259)
Affinity DataKi:  59nMAssay Description:Binding affinity of the compound against p-hydroxybenzoate hydroxylase (PHBH) from Pseudomonas fluorescence competing with p-hydroxy benzoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  61nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetp-hydroxybenzoate hydroxylase(Pseudomonas fluorescens)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50038194(2-Benzyloxy-4-hydroxy-benzoic acid | CHEMBL130259)
Affinity DataKi:  69nMAssay Description:Binding affinity of the compound against p-hydroxybenzoate hydroxylase (PHBH) from Pseudomonas fluorescence competing with NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM42467((2R,3R,4S,5R)-2-(6-anilino-9-purinyl)-5-(hydroxyme...)
Affinity DataKi:  110nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50241166((2R,3R,4S,5R)-2-(6-(benzylamino)-9H-purin-9-yl)-5-...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50008413(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  157nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50241166((2R,3R,4S,5R)-2-(6-(benzylamino)-9H-purin-9-yl)-5-...)
Affinity DataKi:  350nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011216(1-Methyl-8-(1-methyl-2-phenyl-ethyl)-1,3-dipropyl-...)
Affinity DataKi:  644nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)
Affinity DataKi:  700nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  848nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)
Affinity DataKi:  1.31E+3nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50004938(3-Carboxymethylsulfanyl-4,6-dichloro-1H-indole-2-c...)
Affinity DataIC50:  100nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50038184(3-(Benzoyl-methyl-amino)-6-chloro-1H-indole-2-carb...)
Affinity DataIC50:  110nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015622(1-(2-Thiophen-2-yl-ethyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  114nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015620(1-(2-Thiophen-3-yl-ethyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataIC50:  140nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
LigandPNGBDBM50280002(4,6-Dichloro-3-(oxalyl-amino)-1H-indole-2-carboxyl...)
Affinity DataIC50:  170nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50280003(3-(Benzoyl-methyl-amino)-4,6-dichloro-1H-indole-2-...)
Affinity DataIC50:  270nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280005(3-(Benzoyl-carboxymethyl-amino)-4,6-dichloro-1H-in...)
Affinity DataIC50:  400nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015617(1-[2-(5-Methyl-thiophen-2-yl)-ethyl]-1,3-dihydro-i...)
Affinity DataIC50:  491nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015621(1-(5-Chloro-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015619(1-(3-Thiophen-2-yl-propyl)-1,3-dihydro-imidazole-2...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50280001(3-Benzoylamino-6-chloro-1H-indole-2-carboxylic aci...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015624(1-(4-Thiophen-2-yl-butyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015627(1-(5-Fluoro-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015626(1-Thiophen-2-ylmethyl-1,3-dihydro-imidazole-2-thio...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015625(1-Thiophen-3-ylmethyl-1,3-dihydro-imidazole-2-thio...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015623(1-(5-Methyl-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015618(1-Furan-2-ylmethyl-1,3-dihydro-imidazole-2-thione ...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50280006(4,6-Dichloro-3-(methyl-oxalyl-amino)-1H-indole-2-c...)
Affinity DataIC50:  9.50E+3nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280004(3-Benzoylamino-4,6-dichloro-1H-indole-2-carboxylic...)
Affinity DataIC50:  1.70E+4nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Targetp-hydroxybenzoate hydroxylase(Pseudomonas fluorescens)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50038195(3-Benzyloxy-4-hydroxy-benzoic acid | CHEMBL130260)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration against p-hydroxybenzoate hydroxylase (PHBH) from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed