TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Icahn School of Medicine At Mount Sinai
Affinity DataIC50: 5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
Affinity DataIC50: 504nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
The Research Institute Of The Mcgill University Health Center/Glen Hospital
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 8 mins in presence of ATP by colorimetric analysisMore data for this Ligand-Target Pair
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Icahn School of Medicine At Mount Sinai
Affinity DataIC50: 1.60E+3nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 144nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 85nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 163nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 264nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 191nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 380nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 129nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 4.33E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 1.58E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 0.0320nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetDelta-type/Mu-type opioid receptor(MOUSE)
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 0.0316nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 83nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 945nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 426nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 2.65E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 2.15E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 119nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 605nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 61nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 172nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 3.33E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 1.02E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 93nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 374nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 659nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 288nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 812nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 509nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 960nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
St Louis College Of Pharmacy And Washington University
Curated by ChEMBL
Affinity DataEC50: 205nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
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