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Found 2930 with Last Name = 'hert' and Initial = 'j'
TargetMelanocortin receptor 4(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165935(Ac-YRMEHdFRWGSPPKD-NH2 | CHEMBL414718)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.100nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165935(Ac-YRMEHdFRWGSPPKD-NH2 | CHEMBL414718)
Affinity DataKi:  0.110nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  0.140nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165932(Ac-YRMEHdFRWG-NH2 | CHEMBL266879)
Affinity DataKi:  0.210nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.230nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165935(Ac-YRMEHdFRWGSPPKD-NH2 | CHEMBL414718)
Affinity DataKi:  0.260nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165935(Ac-YRMEHdFRWGSPPKD-NH2 | CHEMBL414718)
Affinity DataKi:  0.270nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165927(Ac-YR[CEH(pF-dF)RWC]-NH2 | CHEMBL407809)
Affinity DataKi:  0.280nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165924(Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2 | CHEMBL412523)
Affinity DataKi:  0.300nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.310nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  0.390nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419411(CHEMBL1915012)
Affinity DataKi:  0.398nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO-K1 cells assessed as inhibition of PGE2-mediated intracellular calcium mobiliz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165941(Ac-R[CEHdFRWC]-NH2 | CHEMBL408257)
Affinity DataKi:  0.440nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165933(CHEMBL428326 | GPYRMEHFRWGSPPKD-NH2)
Affinity DataKi:  0.510nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165926(Ac-YR[CEHdFRWC]SPPKD-NH2 | CHEMBL2373515)
Affinity DataKi:  0.520nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165930(Ac-YR[CEHdFRWC]-NH2 | CHEMBL264352)
Affinity DataKi:  0.520nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165932(Ac-YRMEHdFRWG-NH2 | CHEMBL266879)
Affinity DataKi:  0.550nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  0.550nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165926(Ac-YR[CEHdFRWC]SPPKD-NH2 | CHEMBL2373515)
Affinity DataKi:  0.570nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165930(Ac-YR[CEHdFRWC]-NH2 | CHEMBL264352)
Affinity DataKi:  0.770nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50373326(CHEMBL444278)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to human P2Y1 receptorMore data for this Ligand-Target Pair
TargetMelanocortin receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165932(Ac-YRMEHdFRWG-NH2 | CHEMBL266879)
Affinity DataKi:  0.840nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165939(AEKKDEGPYRMEHFRWGSPPKD | CHEMBL412536)
Affinity DataKi:  0.890nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165932(Ac-YRMEHdFRWG-NH2 | CHEMBL266879)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
Hypha Discovery

Curated by ChEMBL
LigandPNGBDBM50301021((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...)
Affinity DataKi:  2nMAssay Description:Inhibition of VMAT2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
Hypha Discovery

Curated by ChEMBL
LigandPNGBDBM50301021((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...)
Affinity DataKi:  2nMAssay Description:Inhibition of VMAT2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165928(Ac-[CEHdFRWC]-NH2 | CHEMBL385556)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165938(Ac-YCit[CEHdFRWC]-NH2 | CHEMBL412494)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165940(Ac-YRC(Me)*EHdFRWC(Me)NH2 | CHEMBL427666)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  3.10nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165933(CHEMBL428326 | GPYRMEHFRWGSPPKD-NH2)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataKi:  6.60nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165924(Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2 | CHEMBL412523)
Affinity DataKi:  6.80nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165926(Ac-YR[CEHdFRWC]SPPKD-NH2 | CHEMBL2373515)
Affinity DataKi:  7.90nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  8.20nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165939(AEKKDEGPYRMEHFRWGSPPKD | CHEMBL412536)
Affinity DataKi:  8.20nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165933(CHEMBL428326 | GPYRMEHFRWGSPPKD-NH2)
Affinity DataKi:  9.20nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
Hypha Discovery

Curated by ChEMBL
LigandPNGBDBM50342820((2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,1...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of VMAT2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165927(Ac-YR[CEH(pF-dF)RWC]-NH2 | CHEMBL407809)
Affinity DataKi:  9.90nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165941(Ac-R[CEHdFRWC]-NH2 | CHEMBL408257)
Affinity DataKi:  10nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50373304(CHEMBL255724)
Affinity DataKi:  10nMAssay Description:Binding affinity to human P2Y1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165939(AEKKDEGPYRMEHFRWGSPPKD | CHEMBL412536)
Affinity DataKi:  11nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))TBA
LigandPNGBDBM50197092(CHEMBL3947458)
Affinity DataKi:  12nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237034(CHEMBL4061626)
Affinity DataKi:  12nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237035(CHEMBL4099881)
Affinity DataKi:  13nMAssay Description:Inhibition of human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165940(Ac-YRC(Me)*EHdFRWC(Me)NH2 | CHEMBL427666)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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