Report error Found 170 with Last Name = 'gutierrez' and Initial = 'ja'
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 0.0700nM ΔG°: -58.0kJ/molepH: 7.5 T: 25°CAssay Description:Purified MTAN activity in MTAN enzyme inhibition assayMore data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 0.0730nM ΔG°: -57.9kJ/molepH: 7.5 T: 25°CAssay Description:Purified MTAN activity in MTAN enzyme inhibition assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 0.208nM ΔG°: -55.3kJ/molepH: 7.5 T: 25°CAssay Description:Purified MTAN activity in MTAN enzyme inhibition assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Mixed noncompetitive inhibition of recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 368nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 602nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of 1 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5Assay Description:For determination of IC50 values for LYPLAL1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.5Assay Description:For determination of IC50 values for LYPLAL1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of 10 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.5Assay Description:For determination of IC50 values for LYPLAL1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of 1 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 7.5Assay Description:For determination of IC50 values for LYPLAL1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of...More data for this Ligand-Target Pair