Found 132 with Last Name = 'bufton' and Initial = 'jc' TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of DDR2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of DDR2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of DDR1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of DDR1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of p38alpha (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
