Affinity DataIC50: 0.0100nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Rattus norvegicus)
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat ADCY10 overexpressed in rat 4-4 cells assessed as IBMX stimulated cAMP accumulation preincubated for 10 mins followed by IBMX stimu...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Rattus norvegicus)
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat ADCY10 overexpressed in rat 4-4 cells assessed as IBMX stimulated cAMP accumulation preincubated for 10 mins followed by IBMX stimu...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Rattus norvegicus)
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of rat ADCY10 overexpressed in rat 4-4 cells assessed as IBMX stimulated cAMP accumulation preincubated for 10 mins followed by IBMX stimu...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Rattus norvegicus)
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of rat ADCY10 overexpressed in rat 4-4 cells assessed as IBMX stimulated cAMP accumulation preincubated for 10 mins followed by IBMX stimu...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Tri-Institutional Institutional Therapeutics Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair