Found 58 with Last Name = 'norton' and Initial = 'rs' TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Nav1.7 expressed in xenopus oocytes at -80 mV holding potential by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at -80 mV holding potential by QPatch assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2 channel assessed as inhibition of CaV2.2-mediated Ba2+ pe...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 6(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of TRPV6 (unknown origin) expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2 channel assessed as inhibition of CaV2.2-mediated Ba2+ pe...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of Nav1.6 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Nav1.2 (unknown origin) expressed in xenopus oocytes at -80 mV holding potential by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of nAChR epsilon (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Peptides International
Curated by ChEMBL
Peptides International
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in xenopus oocytes at -80 mV holding potential by two-electrode voltage-clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of rat Nav1.4 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus oocytes assessed as inhibition of Ach-evoked current after 5 mins by voltage-clamp techniqueMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus oocytes assessed as inhibition of Ach-evoked current after 5 mins by voltage-clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Rattus norvegicus)
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat Nav1.3 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of rat Nav1.2 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of mouse Nav1.6 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by t...More data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.23E+4nMAssay Description:Inhibition of rat Nav1.2 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
Affinity DataIC50: 5.43E+4nMAssay Description:Inhibition of mouse Nav1.6 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by t...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 5.43E+4nMAssay Description:Inhibition of rat Nav1.4 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Rattus norvegicus)
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of rat Nav1.3 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of rat Nav1.1 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of rat Nav1.7 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 2.04E+5nMAssay Description:Inhibition of rat Nav1.4 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.37E+5nMAssay Description:Inhibition of rat Nav1.5 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.87E+5nMAssay Description:Inhibition of rat Nav1.5 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat Nav1.7 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Rattus norvegicus)
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat Nav1.3 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat Nav1.1 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Rattus norvegicus)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 8.71E+5nMAssay Description:Inhibition of rat Nav1.5 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
Affinity DataKd: 45nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 465nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 99nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 49nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 465nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 99nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 49nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 29nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 442nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 45nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Rattus norvegicus)
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Inhibition of rat Nav1.3 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataKd: 442nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 29nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to recombinant GST-tagged mouse SPSB2 (12 to 224 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
TargetSPRY domain-containing SOCS box protein 2(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKd: 35nMAssay Description:Binding affinity to GST-tagged SPSB2 (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR assayMore data for this Ligand-Target Pair
TargetSPRY domain-containing SOCS box protein 2(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKd: 318nMAssay Description:Binding affinity to GST-tagged SPSB2 (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR assayMore data for this Ligand-Target Pair
TargetSPRY domain-containing SOCS box protein 2(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKd: 4.40nMAssay Description:Binding affinity to GST-tagged SPSB2 (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR assayMore data for this Ligand-Target Pair
