Affinity DataIC50: 1.60nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TTBK2 (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of TTBK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of TTBK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Instituto De Quimica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair