BindingDB PrimarySearch_ki

Found 155 with Last Name = 'namkung' and Initial = 'w'

Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)

IC50: 21nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Details US Patent

Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)

IC50: 21nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Details Article PubMed

Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)

IC50: 22nMAssay Description:Inhibition of ANO1 (unknown origin) expressed in FRT cells assessed as reduction in ATP-induced chloride current after 20 mins by electrophysiologica...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Details Article PubMed

Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])

IC50: 77nMAssay Description:Inhibition of ANO1 (unknown origin) expressed in FRT cells assessed as reduction in ATP-induced chloride current after 20 mins by electrophysiologica...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50324734(7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7...)

IC50: 90nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells assessed as inhibition of CPT-cAMP-induced apical membrane current in presence of transepithelial...More data for this Ligand-Target Pair

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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])

IC50: 97nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])

IC50: 97nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503455(CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...)

IC50: 210nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503455(CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...)

IC50: 210nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503439(CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...)

IC50: 300nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Details US Patent

Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50244767(4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)th...)

IC50: 300nMAssay Description:Inhibition of CFTRMore data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503439(CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...)

IC50: 300nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416575(CHEMBL1222175)

IC50: 700nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416577(CHEMBL1081471)

IC50: 800nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50324734(7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7...)

IC50: 800nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416576(CHEMBL1222176)

IC50: 800nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50503453(CHEMBL4577443)

IC50: 890nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair

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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50324734(7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7...)

IC50: <1.00E+3nMAssay Description:Inhibition of CFTR in nonpermeabilized human bronchial epithelial cells assessed as inhibition of forskolin and IBMX-induced chloride current at by s...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50324734(7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7...)

IC50: <1.00E+3nMAssay Description:Inhibition of CFTR in nonpermeabilized human T84 cells assessed as inhibition of forskolin and IBMX-induced chloride current by short-circuit current...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416580(CHEMBL1080548)

IC50: 1.20E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416579(CHEMBL1222277)

IC50: 1.20E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416581(CHEMBL1222278)

IC50: 1.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416578(CHEMBL1222276)

IC50: 1.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416582(CHEMBL1222337)

IC50: 1.70E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416588(CHEMBL1222405)

IC50: 1.70E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416587(CHEMBL1222404)

IC50: 1.70E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416591(CHEMBL1221482)

IC50: 2.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416590(CHEMBL1221481)

IC50: 2.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416589(CHEMBL1222406)

IC50: 2.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416583(CHEMBL1222338)

IC50: 2.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416592(CHEMBL1221483)

IC50: 2.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416593(CHEMBL1221484)

IC50: 2.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416584(CHEMBL1222339)

IC50: 2.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387382(CHEMBL2047095)

IC50: 2.80E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416594(CHEMBL1221530)

IC50: 3.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416595(CHEMBL1221531)

IC50: 3.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387384(CHEMBL2047098)

IC50: 3.20E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387388(CHEMBL2047097)

IC50: 3.20E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387370(CHEMBL2047083)

IC50: 3.30E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387378(CHEMBL2047091)

IC50: 3.80E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416585(CHEMBL1222340)

IC50: 4.50E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387380(CHEMBL2047093)

IC50: 4.90E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416596(CHEMBL1221532)

IC50: 5.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50324733(CHEMBL1221576 | N'-(3,5-dibromo-2,4-dihydroxybenzy...)

IC50: 5.00E+3nMAssay Description:Inhibition of CFTRMore data for this Ligand-Target Pair

PDB Reactome pathway
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387385(CHEMBL2047099)

IC50: 5.20E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387361(CHEMBL2046973)

IC50: 5.90E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387376(CHEMBL2047089)

IC50: 6.30E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387381(CHEMBL2047094)

IC50: 7.70E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Cystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL

PNG

BDBM50416597(CHEMBL1221533)

IC50: 8.00E+3nMAssay Description:Inhibition of human CFTR expressed in rat FRT cells coexpressing halide indicator YFP-H148Q assessed as inhibition of halide influx preincubated for ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Anoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent

PNG

BDBM50387374(CHEMBL2047087)

IC50: 9.00E+3nMAssay Description:Inhibition of human TMEM16A transfected in FRT cells assessed as iodide influx using YFP-F46L/H148Q/I152L halide sensor after 10 mins by spectrofluor...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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