TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.640nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1(Thr37/46) peptide as substrate measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human PI3K p120gamma using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1(Thr37/46) peptide as substrate measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 5nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 7nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 8nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 8nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 8nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 8nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 9nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 9nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 9nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 10nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 10nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 10nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 10nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 11nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 12nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 12nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 12nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Wuxi Apptec (Shanghai) Co.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 14nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 14nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 15nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 15nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 16nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
US Patent
Affinity DataIC50: 16nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair