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Found 2842 with Last Name = 'ban' and Initial = 'h'
TargetApelin(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50009575(CHEMBL3234446)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-pE13F from human apelin receptor expressed in CHO cell membranes after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252994(US9469608, 23-4b)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284388(2-{[Acetyl-(1-hexadecylcarbamoyloxymethyl-cyclopen...)
Affinity DataKi:  1.20nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253006(US9469608, 34-7)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253008(US9469608, 36-3)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM230672(US9340530, 10)
Affinity DataKi:  3nMpH: 7.5Assay Description:Thrombin receptor antagonists were screened using a modification of the thrombin receptor radioligand binding assay of Ahn et al. (Ahn et al., Mol. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM230664(US9340530, 2)
Affinity DataKi:  3nMpH: 7.5Assay Description:Thrombin receptor antagonists were screened using a modification of the thrombin receptor radioligand binding assay of Ahn et al. (Ahn et al., Mol. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM230675(US9340530, 13)
Affinity DataKi:  3nMpH: 7.5Assay Description:Thrombin receptor antagonists were screened using a modification of the thrombin receptor radioligand binding assay of Ahn et al. (Ahn et al., Mol. P...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253013(US9469608, 39-10b)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252985(US9469608, 13-10)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253012(US9469608, 39-10a)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253004(US9469608, 32-7)
Affinity DataKi:  3.90nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284401(2-{[Acetyl-(1-octadecylcarbamoyloxymethyl-cyclopen...)
Affinity DataKi:  4.20nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284419(2-{[Acetyl-((2R,4R)-4-octadecylcarbamoyloxymethyl-...)
Affinity DataKi:  4.30nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284416(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-cyclobut...)
Affinity DataKi:  4.30nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253003(US9469608, 31-7)
Affinity DataKi:  4.80nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284417(2-{[Acetyl-((2R,4R)-4-octadecylcarbamoyloxymethyl-...)
Affinity DataKi:  5.70nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284395(2-{[Acetyl-(1-octadecylcarbamoyloxymethyl-cyclobut...)
Affinity DataKi:  6.60nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50005232((R)-2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-...)
Affinity DataKi:  7.20nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50005232((R)-2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-...)
Affinity DataKi:  7.20nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252990(US9469608, 20-8)
Affinity DataKi:  7.70nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252995(US9469608, 24-8)
Affinity DataKi:  9.20nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284414(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Affinity DataKi:  9.20nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284399(1-[4-(1-Octadecylcarbamoyloxymethyl-cyclopentylmet...)
Affinity DataKi:  9.40nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252984(US9469608, 11-2)
Affinity DataKi:  9.70nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284412(2-{[Acetyl-((2S,4S)-4-hexadecylcarbamoyloxymethyl-...)
Affinity DataKi:  9.80nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284420(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Affinity DataKi:  9.80nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM253002(US9469608, 30-6)
Affinity DataKi:  11nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284409(2-{[Acetyl-(2,2-dimethyl-3-octadecylcarbamoyloxy-p...)
Affinity DataKi:  13nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252982(US9469608, 9-2)
Affinity DataKi:  13nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284414(2-{[Acetyl-((2S,4R)-4-octadecylcarbamoyloxymethyl-...)
Affinity DataKi:  15nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252991(US9469608, 21-6)
Affinity DataKi:  15nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284422(2-{[Acetyl-((2S,4S)-4-hexadecyloxymethyl-oxetan-2-...)
Affinity DataKi:  15nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252999(US9469608, 28-6)
Affinity DataKi:  16nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252980(US9469608, 7-1)
Affinity DataKi:  17nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252983(US9469608, 10-7)
Affinity DataKi:  17nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252981(US9469608, 8-8)
Affinity DataKi:  18nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284423(2-{[Acetyl-((2R,4R)-4-hexadecyloxymethyl-thietan-2...)
Affinity DataKi:  20nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284386(1-[5-(3-Octadecylcarbamoyloxymethyl-thietan-3-ylme...)
Affinity DataKi:  20nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284400(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Affinity DataKi:  20nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252998(US9469608, 27-9)
Affinity DataKi:  20nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252978(US9469608, 5-9 | US9469608, 6-2)
Affinity DataKi:  21nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284413(2-{[Acetyl-((2S,4R)-4-hexadecyloxymethyl-oxetan-2-...)
Affinity DataKi:  21nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252987(US9469608, 15-8)
Affinity DataKi:  22nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252986(US9469608, 14-5)
Affinity DataKi:  22nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284400(2-{[Acetyl-(3-octadecylcarbamoyloxymethyl-oxetan-3...)
Affinity DataKi:  23nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252974(US9469608, 1-12)
Affinity DataKi:  25nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284415(1-Ethyl-2-{[((2R,4R)-4-hexadecylcarbamoyloxymethyl...)
Affinity DataKi:  26nMAssay Description:In vitro ability to displace [3H]-PAF from PAF receptor in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM252977(US9469608, 4-5)
Affinity DataKi:  27nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284398(3-[5-(3-Octadecylcarbamoyloxymethyl-thietan-3-ylme...)
Affinity DataKi:  28nMAssay Description:Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
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