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Found 145 with Last Name = 'bodnarchuk' and Initial = 'ms'
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559562(CHEMBL4762834)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559561(CHEMBL4760006)
Affinity DataKi:  3.13E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559558(CHEMBL4764936)
Affinity DataKi:  4.06E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559555(CHEMBL4745988)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559556(CHEMBL4749889)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559557(CHEMBL4794689)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559559(CHEMBL4746129)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559560(CHEMBL4756804)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559552(CHEMBL4776002)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559563(CHEMBL4776454)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559564(CHEMBL4746167)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559565(CHEMBL4776453)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559566(CHEMBL4749721)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559567(CHEMBL4760989)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559568(CHEMBL4748733)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559569(CHEMBL4761199)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559570(CHEMBL4760832)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559571(CHEMBL4793389)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559572(CHEMBL4747047)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559573(CHEMBL4741361)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559574(CHEMBL4785438)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559575(CHEMBL4798439)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559576(CHEMBL4794850)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559577(CHEMBL4797456)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559554(CHEMBL4751454)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559578(CHEMBL4751618)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559551(CHEMBL4758612)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Antabio

Curated by ChEMBL
LigandPNGBDBM50559553(CHEMBL4745918)
Affinity DataKi: >5.70E+4nMAssay Description:Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539187(CHEMBL4632769)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502619(CHEMBL4561264)
Affinity DataIC50:  0.398nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502622(CHEMBL4579467)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388722(CHEMBL2059865)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605537(CHEMBL5183988)
Affinity DataIC50:  3nMAssay Description:Inhibition of C-terminal Avi and 6His-tagged human KRAS 2B G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhib...More data for this Ligand-Target Pair
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605543(CHEMBL5207711)
Affinity DataIC50: <5nMAssay Description:Inhibition of C-terminal Avi and 6His-tagged human KRAS 2B G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527057(CHEMBL4461434)
Affinity DataIC50: <5nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502621(CHEMBL4513306)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605540(CHEMBL5171553)
Affinity DataIC50:  9nMAssay Description:Inhibition of C-terminal Avi and 6His-tagged human KRAS 2B G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527051(CHEMBL4591572)
Affinity DataIC50:  16nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527059(CHEMBL4452974)
Affinity DataIC50:  18nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50521249(CHEMBL4452819)
Affinity DataIC50:  19nMAssay Description:Inhibition of C-terminal Avi and 6His-tagged human KRAS 2B G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50605537(CHEMBL5183988)
Affinity DataIC50:  36nMAssay Description:Inhibition of p90RSK phosphorylation in human NCI-H358 cells harboring KRAS G12C mutant measured for 2 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502616(CHEMBL4564319)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502617(CHEMBL4570759)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527058(CHEMBL4455191)
Affinity DataIC50:  52nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527050(CHEMBL4572730)
Affinity DataIC50:  70nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527054(CHEMBL4453777)
Affinity DataIC50:  73nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527054(CHEMBL4453777)
Affinity DataIC50:  73nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50502620(CHEMBL4451898)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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