TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKi: 148nMAssay Description:Inhibition of HMGB1 binding to human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of S110B binding to human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometryMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli JM109 cellsMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 7.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometryMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based non competitive inhibition type assayMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based mixed inhibition type assayMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductaseMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based mixed inhibition type assayMore data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Alma Mater Studiorum-Bologna University
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based non competitive inhibition type assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Displacement of [I125]amyloid beta (1 to 40) from human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 32nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 2.40E+7nMAssay Description:Inhibition of amyloid beta binding to human RAGE domain V (Met1 to Ala 344 residues) expressed in HEK293 cells after 10 mins by MST assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Inhibition of amyloid beta (1 to 42) binding to RAGE domain V (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 3nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 6nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 15nMAssay Description:Binding affinity to human RAGE domain V by autoradiographyMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence...More data for this Ligand-Target Pair
TargetAdvanced glycosylation end product-specific receptor(Rattus norvegicus)
King'S College London
Curated by ChEMBL
King'S College London
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to Wistar rat His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair