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Found 37 with Last Name = 'bongarzone' and Initial = 's'
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249567(CHEMBL4075936)
Affinity DataKi:  25nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249567(CHEMBL4075936)
Affinity DataKi:  148nMAssay Description:Inhibition of HMGB1 binding to human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249567(CHEMBL4075936)
Affinity DataKi:  230nMAssay Description:Inhibition of S110B binding to human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50170726(4,4'-Bis(4-benzyloxy-3-methoxybenzimidoylamino)dic...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli JM109 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50158584(2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50293570(2-{4-[4-Amino-6,7-bis-(2-dimethylamino-ethoxy)-qui...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based non competitive inhibition type assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50170726(4,4'-Bis(4-benzyloxy-3-methoxybenzimidoylamino)dic...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based mixed inhibition type assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50158584(2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based mixed inhibition type assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50293569(2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi recombinant trypanothione reductase by spectrophotometry-based non competitive inhibition type assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249569(CHEMBL4063487)
Affinity DataIC50: <500nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249569(CHEMBL4063487)
Affinity DataIC50: <500nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249568(CHEMBL4068269)
Affinity DataIC50: <500nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249568(CHEMBL4068269)
Affinity DataIC50: <500nMAssay Description:Displacement of [I125]amyloid beta (1 to 40) from human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249568(CHEMBL4068269)
Affinity DataIC50: <500nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249569(CHEMBL4063487)
Affinity DataIC50: <500nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249578(CHEMBL4095634)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of S110B binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50005634(CHEMBL3235375)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249578(CHEMBL4095634)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249578(CHEMBL4095634)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249582(CHEMBL1547178 | US10729695, Compound CB-13)
Affinity DataKd:  32nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249581(CHEBI:6700 | Matrine)
Affinity DataKd:  2.40E+7nMAssay Description:Inhibition of amyloid beta binding to human RAGE domain V (Met1 to Ala 344 residues) expressed in HEK293 cells after 10 mins by MST assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataKd:  500nMAssay Description:Inhibition of amyloid beta (1 to 42) binding to RAGE domain V (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249579(CHEMBL1477694 | US10729695, Compound CB-3)
Affinity DataKd:  1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249577(CHEMBL4072531 | US10729695, Compound CB-4)
Affinity DataKd:  2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249576(CHEMBL4075539 | US10729695, Compound CD-6)
Affinity DataKd:  4nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249575(CHEMBL4100986 | US10729695, Compound CB-10)
Affinity DataKd:  3nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249574(CHEMBL4077165 | US10729695, Compound CB-5)
Affinity DataKd:  1nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249573(CHEMBL4063929)
Affinity DataKd:  2nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249572(CHEMBL1463447 | US10729695, Compound CB-1)
Affinity DataKd:  6nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249571(CHEMBL4101927 | US10729695, Compound CB-6)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human RAGE cytoplasmic domain by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249570(CHEMBL4066660)
Affinity DataKd:  15nMAssay Description:Binding affinity to human RAGE domain V by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM26115(CHEMBL286204 | Quinolinate | Quinolinic acid | pyr...)
Affinity DataKd:  43nMAssay Description:Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249566(CHEMBL4085254)
Affinity DataKd:  30nMAssay Description:Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Rattus norvegicus)
King'S College London

Curated by ChEMBL
LigandPNGBDBM26115(CHEMBL286204 | Quinolinate | Quinolinic acid | pyr...)
Affinity DataKd:  43nMAssay Description:Binding affinity to Wistar rat His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed