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Found 332 with Last Name = 'cohen' and Initial = 'p'
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031347(2-Amino-5-(2-amino-propyl)-benzene-1,4-diol | CHEM...)
Affinity DataKi:  1nMAssay Description:Evaluated for the Non competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130461(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031347(2-Amino-5-(2-amino-propyl)-benzene-1,4-diol | CHEM...)
Affinity DataKi:  3nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031343(2-Amino-5-(2-amino-ethyl)-benzene-1,4-diol | CHEMB...)
Affinity DataKi:  5nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119543(CHEMBL3617549)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031341(4-Amino-5-(2-amino-propyl)-benzene-1,2-diol | CHEM...)
Affinity DataKi:  8nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119542(CHEMBL3617550)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031343(2-Amino-5-(2-amino-ethyl)-benzene-1,4-diol | CHEMB...)
Affinity DataKi:  9nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031341(4-Amino-5-(2-amino-propyl)-benzene-1,2-diol | CHEM...)
Affinity DataKi:  9nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119532(CHEMBL3617557)
Affinity DataKi:  9.5nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031344(4-Amino-5-(2-amino-ethyl)-benzene-1,2-diol | CHEMB...)
Affinity DataKi:  11nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM81264(5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide |...)
Affinity DataKi:  12nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031346(4-Amino-6-(2-amino-ethyl)-benzene-1,3-diol | CHEMB...)
Affinity DataKi:  13nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031342(5-(2-Amino-propyl)-benzene-1,2,4-triol | 5-(2-Amin...)
Affinity DataKi:  16nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031344(4-Amino-5-(2-amino-ethyl)-benzene-1,2-diol | CHEMB...)
Affinity DataKi:  17nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130461(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Affinity DataKi:  22nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031342(5-(2-Amino-propyl)-benzene-1,2,4-triol | 5-(2-Amin...)
Affinity DataKi:  26nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119540(CHEMBL3617552)
Affinity DataKi:  41nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031348(4-Amino-6-(2-amino-propyl)-benzene-1,3-diol | CHEM...)
Affinity DataKi:  46nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031346(4-Amino-6-(2-amino-ethyl)-benzene-1,3-diol | CHEMB...)
Affinity DataKi:  47nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM81264(5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide |...)
Affinity DataKi:  51nMAssay Description:Evaluated for the Competitive inhibition of uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNinein(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50031348(4-Amino-6-(2-amino-propyl)-benzene-1,3-diol | CHEM...)
Affinity DataKi:  112nMAssay Description:Evaluated for the Competitive inhibition of uptake of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNinein(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNinein(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  230nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataKi:  250nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataKi:  330nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  470nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  470nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119539(CHEMBL3617553)
Affinity DataKi:  530nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataKi:  590nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119535(CHEMBL3616488)
Affinity DataKi:  610nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataKi:  670nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKi:  730nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119537(CHEMBL3617555)
Affinity DataKi:  870nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  1.06E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119533(CHEMBL3617556)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKi:  1.29E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119541(CHEMBL3617551)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119538(CHEMBL3617554)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119530(CHEMBL3617560)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataKi:  3.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119531(CHEMBL3617559)
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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