Affinity DataKi: 1.39E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
Affinity DataKi: 1.93E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
Affinity DataKi: 2.54E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human PDE4B2More data for this Ligand-Target Pair
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release by spec...More data for this Ligand-Target Pair
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release by spec...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release by spec...More data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 9.59E+3nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release by spec...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrop...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate incubated for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate incubated for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human PDE4B2More data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Jordan University Of Science And Technology
Curated by ChEMBL
Jordan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release by spec...More data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human PDE4B2More data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+4nMAssay Description:Inhibition of human recombinant calmodulin assessed as inhibition of calmodulin-sensitive cAMP phosphodiesterase activation after 15 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of AGR quorum sensing system in methicillin-resistant Staphylococcus aureus AH2759 incubated for 15 hrs by P3-LUX reporter gene assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human PDE4B2More data for this Ligand-Target Pair
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 5.47E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 5.47E+4nMAssay Description:Inhibition of Calmodulin-dependent PDE1 activity assessed as inorganic phosphate release after 30 minMore data for this Ligand-Target Pair