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Target
Accessory gene regulator protein A
Ligand
BDBM115127
Substrate
n/a
Meas. Tech.
ChEMBL_1366621 (CHEMBL3296715)
IC50
30600±n/a nM
Citation
 Figueroa, M; Jarmusch, AK; Raja, HA; El-Elimat, T; Kavanaugh, JS; Horswill, AR; Cooks, RG; Cech, NB; Oberlies, NH Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod 77:1351-8 (2014) [PubMed]  Article 
Target
Name:
Accessory gene regulator protein A
Synonyms:
AGRA_STAAU | agrA | agr
Type:
PROTEIN
Mol. Mass.:
27903.57
Organism:
Staphylococcus aureus
Description:
ChEMBL_1366621
Residue:
238
Sequence:
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
  
Inhibitor
Name:
BDBM115127
Synonyms:
MLS000876948 | 4,5,7-trihydroxy-9,10-dioxo-2-anthracenecarboxylic acid | 4,5,7-trihydroxy-9,10-dioxoanthracene-2-carboxylic acid | 4,5,7-tris(oxidanyl)-9,10-bis(oxidanylidene)anthracene-2-carboxylic acid | SMR000440655 | cid_361510 | 4,5,7-trihydroxy-9,10-diketo-anthracene-2-carboxylic acid
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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