TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 160nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 7.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 2.40E+4nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+5nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+5nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 430nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 930nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis Measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assay; Partial a...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataEC50: >3.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human Metabotropic glutamate receptor 2 expressed in recombinant mammalian cells by GTPgammaS bindin...More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Agonistic activity of the compound was tested on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair