TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:TP_TRANSPORTER: inhibition pramipexole uptake in rOCT1-injected oocytesMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+4nMAssay Description:TP_TRANSPORTER: inhibition pramipexole uptake in rOCT2-injected oocytesMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 13(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ADAMTS-13 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 13(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ADAMTS-13 (unknown origin)More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Bos taurus)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Ex vivo inhibition of ADAMTS-5-mediated aggrecan degradation in IL-1-stimulated bovine cartilage explantMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of MMP14 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP14 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin) by FRET methodMore data for this Ligand-Target Pair
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Nippon Boehringer Ingelheim
Curated by ChEMBL
Nippon Boehringer Ingelheim
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillat...More data for this Ligand-Target Pair
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Nippon Boehringer Ingelheim
Curated by ChEMBL
Nippon Boehringer Ingelheim
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [ethyl 1-14C]TEA substrate uptake at 100 uM by liquid scintill...More data for this Ligand-Target Pair
Affinity DataIC50: 7.63E+4nMAssay Description:TP_TRANSPORTER: inhibition pramipexole uptake in rOCT1-injected oocytesMore data for this Ligand-Target Pair
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Nippon Boehringer Ingelheim
Curated by ChEMBL
Nippon Boehringer Ingelheim
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillat...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Nippon Boehringer Ingelheim
Curated by ChEMBL
Nippon Boehringer Ingelheim
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction of [3H]E-sul substrate uptake by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Nippon Boehringer Ingelheim
Curated by ChEMBL
Nippon Boehringer Ingelheim
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells assessed as reduction of [3H]E217betaG substrate uptake by liquid scintillation coun...More data for this Ligand-Target Pair