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Found 1720 with Last Name = 'janowsky' and Initial = 'a'
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  0.680nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  0.730nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50568920(CHEMBL4846823)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50568920(CHEMBL4846823)
Affinity DataKi:  0.741nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(CHEMBL460407 | trans-2-Aminomethyl-5-((2''-methoxy...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  0.830nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118272(5-(4-Chloro-phenyl)-9-fluoro-2,5-dihydro-3H-imidaz...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202396((RR/SS)-2-[1-(3,4-dichlorophenyl)butyl]piperidine ...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202396((RR/SS)-2-[1-(3,4-dichlorophenyl)butyl]piperidine ...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202400((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-p...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202400((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-p...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50055017(7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-im...)
Affinity DataKi:  1.05nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362863(CHEMBL1940418)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50237599(CHEMBL4066427)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202391((RS/SR)-methyl 2-(3,4-dichlorophenyl)-2-(piperidin...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202391((RS/SR)-methyl 2-(3,4-dichlorophenyl)-2-(piperidin...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50020222((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane domain-containing protein TMIGD3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50236785(CHEMBL4090355)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3AR expressed in HEK293T cells pre-incubated for 10 mins be...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  1.70nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Dopamine transporter site on HEK cells expressing cDNA for the human transporter (hDAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane domain-containing protein TMIGD3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50116878(CHEMBL3612940)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3AR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50020222((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276645(2-Aminoethyl-5-(3'-(2''-methoxy-5''-fluorophenyl)-...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276593(CHEMBL462311 | trans-2-(Aminoethyl)-5-(2'-methoxy-...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50568924(CHEMBL4862180)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50568924(CHEMBL4862180)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50020222((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RR/SS)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RR/SS)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50568921(CHEMBL4871868)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Department of Veterans Affairs Medical Center

Curated by PDSP Ki Database
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
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