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Found 11 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50055003'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  1.70nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Dopamine transporter site on HEK cells expressing cDNA for the human transporter (hDAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  18nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  1nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  1nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  4.20nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter in guinea pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  4.20nMAssay Description:Compound was tested for inhibition of [3H]-WIN- 35,428 binding at the dopamine transporter in brain from guinea pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  4.20nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed