BDBM50055003 6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol::9-(4-Chloro-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-fluoren-9-ol::CHEMBL130477
SMILES OC1(N2CCCN=C2c2ccccc12)c1ccc(Cl)cc1
InChI Key InChIKey=ZGLAJTSGABGHND-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50055003
Affinity DataKi: 1.70nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Dopamine transporter site on HEK cells expressing cDNA for the human transporter (hDAT)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of 5-HT uptake in HEK cells expressing human serotonin transporter (hSERT)More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter in guinea pig striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of NE uptake in HEK cells expressing human noradrenaline transporter (hNET)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was tested for inhibition of [3H]-citalopram binding at the serotonin transporter in rat fore brain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Compound was tested for inhibition of [3H]-WIN- 35,428 binding at the dopamine transporter in brain from guinea pig striatal membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair