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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50055003'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  39nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataKi:  39nMAssay Description:Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  53nMAssay Description:Inhibition of 5-HT uptake in HEK cells expressing human serotonin transporter (hSERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,...)
Affinity DataIC50:  1.04E+3nMAssay Description:Compound was tested for inhibition of [3H]-citalopram binding at the serotonin transporter in rat fore brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed