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Found 8656 with Last Name = 'knox' and Initial = 'je'
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175982(Bz-Lys-Arg-Arg-H | CHEMBL199510)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175984(BZ-Nle-Lys-Arg-(4-guanidinyl)-Phe-H | Bz-Nle-Lys-A...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175976(Bz-Ala-Lys-Arg-Arg-H | CHEMBL197765)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM33259(Bz-NKRR-H | Bz-Nle-Lys-Arg-Arg-H | CHEMBL256877)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175988(Bz-Nle-Lys-Arg-(p-Me)Phe-H | CHEMBL199396)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175987(Bz-Phe-Lys-Arg-Arg-H | CHEMBL199736)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175974(Bz-Nle-Lys-Arg-Trp-H | CHEMBL433993)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175993(Bz-D-Nle-Lys-Arg-Arg-H | CHEMBL201775)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175978(Bz-Nle-Lys-Arg-(p-Ph)Phe-H | CHEMBL381854)
Affinity DataKi:  1.16E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175981(Bz-Arg-Arg-H | CHEMBL197766)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175985(Bz-Nle-Phe-Arg-Arg-H | CHEMBL199582)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175986(Bz-Nle-Lys-Arg-Phe-H | CHEMBL199727)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175968(Bz-Nle-Lys-Arg-(p-CN)Phe-H | CHEMBL200095)
Affinity DataKi:  1.86E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175971(Bz-Nle-Lys-Arg-Lys-H | CHEMBL377076)
Affinity DataKi:  2.05E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175970(Bz-Nle-Ala-Arg-Arg-H | CHEMBL369916)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175975(Bz-Nle-D-Lys-Arg-Arg-H | CHEMBL370138)
Affinity DataKi:  2.86E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175991(Bz-Nle-Lys-Arg-Phg-H | CHEMBL200972)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175990(Bz-Nle-Lys-Phe-Arg-H | CHEMBL435122)
Affinity DataKi:  4.07E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175977(Bz-Nle-Lys-Lys-Arg-H | CHEMBL201609)
Affinity DataKi:  4.13E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175969(Bz-N-Me-Nle-Lys-Arg-Arg-H | CHEMBL382143)
Affinity DataKi:  4.37E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175967(Bz-Nle-Lys-N-Me-Arg-Arg-H | CHEMBL199726)
Affinity DataKi:  4.74E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175980(Bz-Nle-Lys-Arg-D-Arg-H | CHEMBL199352)
Affinity DataKi:  5.10E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175979(Bz-Nle-Pro-Arg-Arg-H | CHEMBL382983)
Affinity DataKi:  6.14E+4nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175965(Bz-Nle-Lys-Pro-Arg-H | CHEMBL199987)
Affinity DataKi:  1.09E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175973(Bz-Nle-N-Me-Lys-Arg-Arg-H | CHEMBL381639)
Affinity DataKi:  1.13E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175989(Bz-Nle-Lys-D-Arg-Arg-H | CHEMBL371447)
Affinity DataKi:  1.15E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175972(Bz-Nle-Lys-Arg-(p-Cl)Phe-H | CHEMBL199531)
Affinity DataKi:  1.38E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175966(Bz-Nle-Lys-Arg-Ala-H | CHEMBL199376)
Affinity DataKi:  1.93E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175992(Bz-Nle-Lys-Arg-homoPhe-H | CHEMBL370338)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50175983(Bz-Nle-Lys-Ala-Arg-H | CHEMBL372963)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibitory activity against dengue 2 NS3 protease fused via a linker to region of NS2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM449620(US10703733, Example 233 | US10988451, Example 233)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449685(US10703733, Example 298 | US11643400, Example 298)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449620(US10703733, Example 233 | US10988451, Example 233)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449685(US10703733, Example 298 | US11643400, Example 298)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602144(US11643400, Example 233)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449686(US10703733, Example 299 | US10988451, Example 298 ...)
Affinity DataIC50:  0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449659(US10703733, Example 272 | US10988451, Example 272 ...)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449627(US10703733, Example 240 | US10988451, Example 240)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449659(US10703733, Example 272 | US10988451, Example 272 ...)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449627(US10703733, Example 240 | US10988451, Example 240)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602151(US11643400, Example 240)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449659(US10703733, Example 272 | US10988451, Example 272 ...)
Affinity DataIC50:  0.0180nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449730(US10703733, Example 343 | US10988451, Example 343 ...)
Affinity DataIC50:  0.0190nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449730(US10703733, Example 343 | US10988451, Example 343 ...)
Affinity DataIC50:  0.0190nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449730(US10703733, Example 343 | US10988451, Example 343 ...)
Affinity DataIC50:  0.0190nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449679(US10703733, Example 292 | US11643400, Example 292)
Affinity DataIC50:  0.0200nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449679(US10703733, Example 292 | US11643400, Example 292)
Affinity DataIC50:  0.0200nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM493822(US10988451, Example 292)
Affinity DataIC50:  0.0200nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM449559(US10703733, Example 172 | US10988451, Example 172 ...)
Affinity DataIC50:  0.0220nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM449559(US10703733, Example 172 | US10988451, Example 172 ...)
Affinity DataIC50:  0.0220nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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