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Found 116 with Last Name = 'lall' and Initial = 'ms'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603960(US11655252, Compound IC)
Affinity DataIC50: >8.58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50:  30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603958(US11655252, Compound IA)
Affinity DataIC50:  33nMAssay Description:Compounds of the invention were evaluated by in vitro methods to determine their respective ability to inhibit the JAK kinases (TYK2, JAK1, JAK2, JAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378451(CHEMBL578362)
Affinity DataIC50:  36nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50423645(Albamycin | Cathomycin | NOVOBIOCIN)
Affinity DataIC50:  37nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603958(US11655252, Compound IA)
Affinity DataIC50:  37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603960(US11655252, Compound IC)
Affinity DataIC50:  44nMAssay Description:Compounds of the invention were evaluated by in vitro methods to determine their respective ability to inhibit the JAK kinases (TYK2, JAK1, JAK2, JAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378443(CHEMBL568020)
Affinity DataIC50:  44nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50:  47nMAssay Description:Compounds of the invention were evaluated by in vitro methods to determine their respective ability to inhibit the JAK kinases (TYK2, JAK1, JAK2, JAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378425(CHEMBL565765)
Affinity DataIC50:  48nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378420(CHEMBL565750)
Affinity DataIC50:  51nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378433(CHEMBL584265)
Affinity DataIC50:  52nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378426(CHEMBL577478)
Affinity DataIC50:  53nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378429(CHEMBL583049)
Affinity DataIC50:  56nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603959(US11655252, Compound IB)
Affinity DataIC50:  59nMAssay Description:Compounds of the invention were evaluated by in vitro methods to determine their respective ability to inhibit the JAK kinases (TYK2, JAK1, JAK2, JAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603960(US11655252, Compound IC)
Affinity DataIC50:  65nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378450(CHEMBL578361)
Affinity DataIC50:  75nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603958(US11655252, Compound IA)
Affinity DataIC50:  80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50:  81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603959(US11655252, Compound IB)
Affinity DataIC50:  82nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378438(CHEMBL577053)
Affinity DataIC50:  92nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378444(CHEMBL568021)
Affinity DataIC50:  96nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378421(CHEMBL578149)
Affinity DataIC50:  97nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378423(CHEMBL583440)
Affinity DataIC50:  98nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378447(CHEMBL577909)
Affinity DataIC50:  113nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378445(CHEMBL565776)
Affinity DataIC50:  117nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378443(CHEMBL568020)
Affinity DataIC50:  119nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378452(CHEMBL583870)
Affinity DataIC50:  132nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378448(CHEMBL577041)
Affinity DataIC50:  137nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603960(US11655252, Compound IC)
Affinity DataIC50:  139nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378445(CHEMBL565776)
Affinity DataIC50:  147nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378430(CHEMBL568019)
Affinity DataIC50:  149nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378427(CHEMBL565572)
Affinity DataIC50:  163nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378435(CHEMBL578336)
Affinity DataIC50:  198nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378436(CHEMBL578991)
Affinity DataIC50:  216nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM603959(US11655252, Compound IB)
Affinity DataIC50:  223nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378437(CHEMBL578992)
Affinity DataIC50:  242nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378453(CHEMBL567804)
Affinity DataIC50:  244nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378426(CHEMBL577478)
Affinity DataIC50:  250nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378439(CHEMBL565741)
Affinity DataIC50:  255nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378451(CHEMBL578362)
Affinity DataIC50:  258nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378441(CHEMBL578138)
Affinity DataIC50:  261nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378428(CHEMBL578120)
Affinity DataIC50:  265nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378450(CHEMBL578361)
Affinity DataIC50:  280nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378440(CHEMBL571734)
Affinity DataIC50:  295nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378434(CHEMBL565971)
Affinity DataIC50:  330nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378428(CHEMBL578120)
Affinity DataIC50:  353nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378429(CHEMBL583049)
Affinity DataIC50:  364nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378453(CHEMBL567804)
Affinity DataIC50:  366nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378427(CHEMBL565572)
Affinity DataIC50:  367nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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